Professor

Dr. wang photo
Dr. Gou-Jen Wang

Dean of College of Engineering, NCHU
Distinguished Professor, Mechanical Engineering, NCHU
Adjunct Professor, Institute of Biomedical Engineering, NCHU

Phone: 04-2284-0725 ext. 320
FAX: 04-2287-7170
E-mail: gjwang@dragon.nchu.edu.tw
Address: Department of Mechanical Engineeirng, National Chung Hsing University, Taichung 40227, Taiwan

Editorial Board
Austin Journal of Biosensors & Bioelectronics
Austin Journal of Nampmedicine & Nanothechnology
Bioengineering
Inventions
The Journal of the Chinese Society of Mechanical Engineers

Education
B.S., Mechanical Engineering, National Taiwan University, 1981
M.S., Mechanical Engineering, UCLA, CA, USA 1986
Ph.D., Mechanical Engineering, UCLA, CA, USA 1991

Professional Experience
Co-founder, Vidabio Inc., 2014/09- (Nanostructured biosensors design and manufacturing)
Vice Director, Biotechnology Center, National Chung-Hsing University, 2014/02-2015/07
Chairman, Graduate Institute of Biomedical Engineering, National Chung-Hsing University, (2007/10-2011/07)
Distinguished Professor, Mechanical Engineering, National Chung-Hsing University, Since 2008
Visiting Scholar, Department of Mechanical Engineering, U. of Washington, WA, USA, 2006/8-2006/12
Visiting Scholar, Department of Mechanical Engineering, U. of Washington, WA, USA, 2003/7-2003/9
Professor, Mechanical Engineering, National Chung-Hsing University, Since 1999
Associate Professor, Mechanical Engineering, National Chung-Hsing University, (1992/02-1999/07)
System Engineer, Dowty Aerospace, Los Angeles, USA (1991/06-1992/02)
Mechanical Engineer, 3D System, Los Angeles, USA (1989/02-1990/06)

Service and Honors
Conference chair-2017 Asia Pacific Symposium on Technology of Plasticity
Conference chair-2016 International Conference on Advanced Manufacturing
Conference chair- 2016 Automation Taiwan
Conference chair- 2016 21th Symposium of Association for Chemical Sensors in Taiwan
Conference Chair: 2008 Microfabrication, Integration and Packaging Conference (Nice, France)
Committee member: Micro & Nano System Division, American Society of Mechanical Engineers, Since 2009
Conference symposium organizer: American Society of Mechanical Engineers, International Conference on Micro- and Nanosystems, Since 2008
Committee member: DTIP of MEMS/MOEMS Conference, Since 2005

Awards
Medal for the year 2017 - International Association of Advanced Materials (IAAM)
13th Innovators-2016 (Taiwan): Four medals (The first person to get four medals in a year)
ASME 2017, 2016, 2015, 2014, 2011 International Conference on Micro/Nano System, The Best paper award.
ASME 2015 International Mechanical Engineering Congress and Exposition-MEMS Division, The Best paper award.
IEEE Trans. on Nanotechnology, 10(2), 2011, Cover page.

Research Interest

Research interests in our lab include Biomedical Engineering and Nano/Micro Fabrication:

1. Biomedical Engineering research achievements are in (1) Nanostructured biosensors & (2) Tissue engineering and regenerative medicine.

Nanostructured biosensors
Electrochemical analysis is a promising method for biosensing. In our current work, a highly sensitive nanostructured electrochemical biosensor based on a 3D sensing element featuring uniformly deposited gold nanoparticles has been developed. A modified anodic aluminum oxide (AAO) barrier-layer surface is used as the template for nickel thin film deposition. After etching the AAO template off, a 3D mold of the concave nano structure array is created. The fabricated 3D nickel mold is further used for replica molding of a nano-structure polycarbonate (PC) substrate by hot embossing. An Au thin film is then sputtered on the PC substrate to form the electrode followed by the deposition of an orderly and uniform gold nanoparticles (GNPs) layer on the 3D Au electrode using electrochemical deposition. The detections of the dust mite antigen Der p2, allergy patient’s serum, allergy disease related gene mutations (SNP and Haplotype), dengue virus-receptor binding, hepatitis B virus DNA, Alzheimer's (AD) Aβ protein have been successfully carried out using electrochemical impedance spectroscopy (EIS) analysis.

AAO

Publications
1
Shen, M. C., Lai, J. C., Hong, C. Y., and Wang, G. J.*, Electrochemical aptasensor for detecting Der p2 allergen using polycarbonate-based double-generation gold nanoparticle chip, Sensing and Bio-Sensing Research, 13, 75-80, (2017)
2
Chen, C. C., Lai, Z. L., Wang, G. J.*,, and Wu, C. Y.**, Polymerase chain reaction-free detection of hepatitis B virus DNA using a nanostructured impedance biosensor, Biosensors & Bioelectronics, 77, 603-608. (2016) (IF=7.78).
3
Tung, Y. T., Chang, C. C.*, Y. L. Lin, Hsieh, S. L., and Wang, G. J.*, Development of double-generation gold nanoparticle chip-based dengue virus detection system combining fluorescence turn-on probes, Biosensors & Bioelectronics, 77-90-98. (2016) (IF=7.78).
4
Tung, Y. T., Wu, M. F., Wang, G. J.*, and Hsieh, S. L**, Nanostructured electrochemical biosensor for the detection of the weak binding between the Dengue Virus and the CLEC5A receptor, Nanomedicine: NBM, 10, 1335-1341 (2014). (IF=5.72)
5
Chin, Y. T., Liao, E. C., Wu, C. C., Wang, G. J.*, and Tsai, J. J.*, Detection of the haplotype mutations of the MD-2 gene promoter associated with Der p2-induced allergy using a nanostructured biosensor, Inter. J. Nanomedicine, 9, 403-412. (2014) (IF=4.30)
6
Chin, Y. T., Liao, E. C., Wu, C. C., Wang, G. J.*, and Tsai, J. J.**, Label-free detection of single-nucleotide polymorphisms associated with myeloid differentiation-2 using a nanostructured biosensor, Biosensors & Bioelectronics, 49, 506-511. (2013) (IF=7.78)
7
Tsai, J. J., Liu, Y. F., Liao, E. C., Chen, J. L, and Wang, G. J.*, Reduction of incubation time and enhancement of analyte adhesion uniformity of impedance biosensors using microvibration method, Sensors & Actuators B: Chemical, 178, 404-411. (2013) (IF=5.401)
8
Liu, Y. F., Tsai, J. J., Chin, Y. T., Liao, E. C., Wu, C. C., Wang, G. J.*, Detection of allergies using a silver nanoparticle modified nanostructured biosensor, Sensors & Actuators B: Chemical, 171-172, 1095-1100. (2012) (IF=5.401)
9
Chen, Y. S., Wu, C. C., Tsai, J. J., and Wang, G. J.*, An electrochemical impedimetric biosensor based on a nanostructured polycarbonate (PC) substrate, Inter. J. Nanomedicine, 7, 133-140 (2012) (IF=4.30)

In addition to the above nanostructured electrochemical biosensor, We team-up with the Phoenix Silicon International Corporation in semiconductor industry to develop a cost effective and high sensitive non-enzymatic glucose biosensor. The sequential fabrication procedures for the proposed simple non-enzymatic glucose biosensor, including silicon wafer cleaning and photoresist coating, exposure and development, thermal melting, and gold thin film sputtering and deposition of GNPs. Measurements showed a 10.2-fold enhancement of the sensing area in comparison with a plain gold electrode. Actual detection of glucose demonstrated that the proposed non-enzymatic glucose biosensor can operate in a linear range of 55.6 M-13.89 mM. It had a sensitivity of 749.2 μA·mM−1·cm−2 and a detection limit of 9 M. When the glucose concentration is less than 100 mg/Dl, the accuracy of the developed glucose biosensor reaches ±0.18 mg/Dl, which is much better than the FDS and ISO 15197 standard of ±20 mg/Dl and ±15 mg/Dl, respectively. The novel glucose biosensor proposed here has several advantages such as being enzyme free, simple to fabricate, low cost, and easy to preserve on a long-term basis. Thus, it can feasibly be used for future clinical applications.

2
 

Publications
1
Hsu, C. W., Su, F. C., Peng, P. Y., Young, H. T., Liao, S., and Wang, G. J.*, Highly sensitive non-enzymatic electrochemical glucose biosensor using a photolithography fabricated micro/nano hybrid structured electrode, Sensors and Actuators B, 230, 559-565. (2016) (IF=5.401)
2
Hsu, C. W., Feng, W. C., Su, F. C., and Wang, G. J.*, A novel electrochemical glucose biosensor with a silicon nanowire array electrode, J. Electrochemical Society, 162(10), B1-B5. (2015) (IF=3.259)
3
Hsu,C. W., Su,F. C., Peng,P. Y., Young,H. T., Yang,M.,and Wang, G. J.*, A novel non-enzymatic electrochemical glucose biosensor based on a simple lithographic process, The ASME 9th International Conference on Micro- and Nanosystems, Boston, MA, USA. (2015). The Best Paper Award.
4
Hsu, C. W., Feng, W. C., Chang, K. J, And Wang, G. J.*, A novel and simple electrochemical glucose biosensor based on a silicon nanowire array electrode, The ASME 8th International Conference on Micro- and Nanosystems, Baffulo, NY, USA. (2014) The Best Paper Award
5
Hsu, C. W. and Wang, G. J.*, Highly sensitive glucose biosensor based on Au–Ni coaxial nanorod array having high aspect ratio, Biosensors & Bioelectronics, 56, 204-209. (2014) (IF=7.78)
6
Liu, H. C., Tsai, C. C. and Wang, G. J.*, Glucose biosensors based on a gold nanodendrite modified screen-printed electrode, Nanotechnology, 24, 215101. (2013) (IF=3.440)
7
Tsai, C. C. and Wang, G. J.*, A glucose biosensor based on a 3D nanostructured gold electrode, J. Electrochemical Society, 160(1), B1-B5. (2013) (IF=3.259)
 

Tissue Engineering and Regenerative Medicine
Our lab has been working on the fabrication of microvessel networks for more than ten years. Currently ongoing studies include the fabrication of a reticular structure scaffold of cylindrical PLGA for the in vitro development of microvascular networks, nerve guidance conduit with a hybrid structure of microfibrous bundle wrapped in a micro/nanostructured membrane, and investigation of the influences of micro/nanopatterning on gel surface on cancer cell interactions.

3
 

The mitochondrion is a very unique organelle found in most eukaryotic cells. In addition to serving as cellular power plants by producing adenosine triphosphate (ATP) through respiration, mitochondria contribute to other physiological functions, including signalling, cellular differentiation, cell death and regulation of cellular metabolism. Reactive oxygen species, which can result from leakage of the high-energy electrons during the cellular respiration process, can cause oxidative stress in the mitochondria and thereby induce mutations of the mitochondrial DNA (mtDNA). These mutations lead to diseases such as tumours, diabetes, cardiovascular disease and age-related neuropathies. Our lab collaborates with Dr. Chin-San Liu (Vice Superintendent, Changhua Christian Hospital, Taiwan) to work on the the issues of precisely detecting oxidative stress induced mtDNA mutations, efficaciously extracting healthy mitochondria from cells, and chronically preserving healthy mitochondria.

mito
Publications
1
Li, C. W. and Wang, G. J.*, Double-layer nerve guide conduit with palisade poly(lactic-co-glycolic acid) tube wrapped by microporous chitosan–collagen composite, The ASME 11th International Conference on Micro- and Nanosystems, Cleveland, OH, USA. (2017). The Best Paper Award.
2
Tung, Y. T., Chang, C. C., Ju, J. C.*, and Wang, G. J.*, Fabrication of a reticular poly(lactide-co-glycolide) cylindrical scaffold for the in vitro development of microvascular networks, Science and Technology of Advanced Materials, 18(1), 163-171, (2017) (SCI, IF=3.789).
3
Peng, S. W., Li, C. W., Chiu, I. M., and Wang, G. J.*, Nerve guidance conduit with a hybrid structure of a PLGA microfibrous bundle wrapped in a micro/nanostructured membrane, Inter. J. Nanomedicine, 12, 421-432. (2017) (SCI, IF=4.3).
4
Tung, Y. T. and and Wang, G. J.*, In vitro development of microvessels using a scaffold of cylindrical PLGA, The ASME 10th International Conference on Micro- and Nanosystems, Charlotte, NC, USA. (2016). The Best Paper Award-3rd place.
5
Li, C. W., Pan, W. T., Ju, J. C., Wang, G. J.*, An endothelial cell conditioned medium embedded in porous PLGA scaffold for the enhancement of mouse embryonic stem cell differentiation, Biomedical Materials, 11, 025015 (12 pages) (2016) (SCI, IF=2.469).
6
Ciudad, P , Dower, R , Nicoli, F , Orfaniotis, G, Maruccia, M , Constantinescu, T , Lin, S. P., Wang, G. J.*, Chen, H. C., Pelvic-perineal reconstruction with the combined transverse upper gracilis and profunda artery perforator (TUG-PAP) flap, Journal of Plastic Reconstructive and Aesthetic Surgery, 69(4), 573-575. (2016) (SCI, IF=2.048)
7
Lin, Y. T., Li, C. W., and Wang, G. J.*, The nano/micro hybrid structures enhancing B35 cell guidance on chitosan, ASME Journal of Nanotechnology in Engineering and Medicine, 6, 030702 (9 pages) (2016).
8
Wu, J. Y., Li,C. W., Tsai, C. H., Chou, C. W., Chen, D. R., and Wang, G. J.*, Synthesis of antibacterial TiO2/PLGA composite biofilms, Nanomedicine: NBM, 10, 1097-1107, (2014) (SCI, IF=5.720).
9
Li, C. W. and Wang, G. J.*, A material-independent cell–environment niche based on micro-reciprocating motion for cell growth enhancement, Biofabrication, 5, 045001. (2013) (IF=5.240)
10
Wang, H. W., Cheng, C. W., Li, C. W., Wu, P. H., and Wang, G. J.*, Hollow three-dimensional endothelialized microvessel networks based on femtosecond laser ablation, Biomedical Microdevices, 15, 879-885. (2013) (IF=2.062)
11
Wang, H. W., Cheng, C. W., Li, C. W., Chang, H. W., Wu, P. H., Wang, G. J.*, Fabrication of pillared PLGA microvessel scaffold using femtosecond laser ablation, Inter. J. Nanomedicine, 7, 1865-1873. (2012). (SCI, IF=4.30)
 

Nano/Micro Fabrication

(1)Anodic Aluminum Oxide (AAO) Fabrication and Application
Anodic aluminum oxide (AAO) membrane, having nano-size porous array of regular hexagonal-shaped cells with straight columnar channels, has been widely used as the template in fabricating one-dimensional nano materials which have controllable orientation. Our group focuses on the fabrications and applications of AAO. Ongoing researches include gold/nickel coaxial nanorods array, nanobiosensor, nano hemispheric nickel array mold, nanostructure biomaterials.

6
272
Au-Ni coaxial nanorods array
Nano-imprinting of photonic crystal
Publications
1
Peng, C. Y., Hsu, C. W., Li, C. W., Wang, G. J.*, Using anodic aluminum oxide film and nanoimprint to produce polymer anti-counterfeit labels, Smart Science, 5(3), 117-122, (2017)
2
Lee, B. Y., Li, C. W. and Wang, G. J.*, Nanoporous anodic aluminum oxide tube encapsulating a microporous chitosan/collagen composite for long-acting drug release, Biomedical Physics & Engineering Express, 1, 045004 (2015)
3
Lee, B. Y., Li, C. W., and Wang, G. J.*, A microporous chitosan/collagen composite encapsulated small tube of nanoporous anodic aluminum oxide for long-acting drug release, 2015 ASME International Mechanical Engineering Congress and Exposition, Houston, TX, USA. (2015). The Best Paper Award-MEMS Division.
4
Hsu, C. W., Li, C. W. and Wang, G. J.*, Fabrication of biocompatible high aspect ratio Au–Ni coaxial nanorod arrays using the electroless Galvanic displacement reaction method, RSC advances, 4, 12127-12132. (2014) (IF =3.289)
5
Chung, I. C., Li, C. W., and Wang, G. J.*, The influence of different nanostructured scaffolds on fibroblast growth, Science and Technology of Advanced Materials, 14, 044401. (2013) (IF =3.789)
6
Tsai, Y. T., Chang, K. J., and Wang, G. J.*, Measurement and control of the ion diffusion coefficient in a nanochannel, Microsystem Technologies, 19, 937-944. (2013) (IF =1.195)
7
Ho, J. Y. and Wang, G. J.*, Fabrication of high aspect ratio nanoporous array on silicon, Microsystem Technologies, 18, 1849-1856. (2012) (IF =1.195)
 

Recent Research Project (3 years)
Project title
Execution duration
Sponsors
Total amount US $
Personal Training Center of Smart Machinery
2017. 9-2019. 1
Ministry of Education (MOE), Taiwan
580,000
Green extraction and long-term storage of healthy mitochondria
2016. 8-2019. 7
Ministry of Science and Technology (MOST), Taiwan
98,000
Investigation of the influences of micro/ nanopatterning on gel surface on cancer cell interactions- Israel-Taiwan SCIENTIFIC RESEARCH COOPERATION
2015. 9-2017. 8
Ministry of Science and Technology (MOST), Taiwan
70,000
Development of photonic crystal structural color based anti-counterfeiting label fabrication techniques
2015. 8-2018. 7
Ministry of Science and Technology (MOST), Taiwan
88,000
Study of glycan-lectin interaction by developing a highly sensitive nanostructured biosensor
2014.10-2017. 9
Ministry of Science and Technology (MOST), Taiwan
80,000
Development of microvessel network organ-on-chip
2014. 8-2016. 7
MOST, Taiwan
60,400
Development of mitochondria encapsulation and preservation technique
2014. 6-2015. 5
Chang-Hua Christian Hospital, Taiwan
16,700
Dust mite allergen detection biochip mass production techniques development
2014. 6-2016. 5
MOST, Taiwan
100,000
Nanotechnology personnel training Project
2012. 6-2015. 5
MOST, Taiwan
180,000
Fabrication of Au/Ni coaxial nanorods and applications on biomedical detectionr
2012. 8-2015. 7
MOST, Taiwan
83,000
Development of a personalized biochip for the allergen gene detection
2012. 1-2014. 12
Ministry of Health, Welfare, Taiwan
233,333
 
Publication Lists
(A) Journal papers

2017

  1. Tseng, Y. T., Li, C. W., and Wang, G. J.*, Template-assisted fabrication of tunable aspect ratio, biocompatible iron oxide pillar arrays, Advanced Materials Letter, accepted, (2017)
  2. Peng, C. Y., Hsu, C. W., Li, C. W., Wang, G. J.*, Using anodic aluminum oxide film and nanoimprint to produce polymer anti-counterfeit labels, Smart Science, 5(3), 117-122, (2017)
  3. Shen, M. C., Lai, J. C., Hong, C. Y., and Wang, G. J.*, Electrochemical aptasensor for detecting Der p2 allergen using polycarbonate-based double-generation gold nanoparticle chip, Sensing and Bio-Sensing Research, 13, 75-80, (2017)
  4. Tung, Y. T., Chang, C. C., Ju, J. C.*, and Wang, G. J.*, Fabrication of a reticular poly(lactide-co-glycolide) cylindrical scaffold for the in vitro development of microvascular networks, Science and Technology of Advanced Materials, 18(1), 163-171, (2017). (SCI, Impact Factor=3.789, 54/274).
  5. Peng, S. W., Li, C. W., Chiu, I. M., and Wang, G. J.*, Nerve guidance conduit with a hybrid structure of a PLGA microfibrous bundle wrapped in a micro/nanostructured membrane, Inter. J. Nanomedicine, 12, 421-432. (2017) (SCI, Impact Factor=4.3, 37/256)

2016

  1. Li, C. W., Pan, W. T., Ju, J. C., Wang, G. J.*, An endothelial cell conditioned medium embedded in porous PLGA scaffold for the enhancement of mouse embryonic stem cell differentiation, Biomedical Materials, 11, 025015 (12 pages) (2016) (SCI, Impact Factor=2.469, 27/77).
  2.  Ciudad, P , Dower, R , Nicoli, F , Orfaniotis, G, Maruccia, M , Constantinescu, T , Lin, S. P.,  Wang, G. J.*, Chen, H. C., Pelvic-perineal reconstruction with the combined transverse upper gracilis and profunda artery perforator (TUG-PAP) flap, Journal of Plastic Reconstructive and Aesthetic Surgery, 69(4), 573-575. (2016) (SCI, Impact Factor=2.048, 84/196)
  3. Hsu, C. W., Su, F. C., Peng, P. Y., Young, H. T., Liao, S., and Wang, G. J.*, Highly sensitive non-enzymatic electrochemical glucose biosensor using a photolithography fabricated micro/nano hybrid structured electrode, Sensors and Actuators B, 230, 559-565. (2016) (SCI, Impact Factor=5.401, 2/58)
  4. Lin, Y. T., Li, C. W., and Wang, G. J.*, The nano/micro hybrid structures enhancing B35 cell guidance on chitosan, ASME Journal of Nanotechnology in Engineering and Medicine, 6, 030702 (9 pages) (2016).
  5. Chang, C. Y., Sasaki, M., Kumagai, S., and Wang, G. J.*, Design of microplasma electrodes for plasma-on-chip devices, Journal of Physics D, Applied Physics, 49, 155203 (8 pages) (2016) (SCI, Impact Factor=2.588, 44/147).
  6. Chen, C. C., Lai, Z. L., Wang, G. J.*,, and Wu, C. Y.**, Polymerase chain reaction-free detection of hepatitis B virus DNA using a nanostructured impedance biosensor, Biosensors & Bioelectronics, 77, 603-608. (2016) (SCI, Impact Factor=7.78, 1/28).
  7. Tung, Y. T., Chang, C. C.*, Y. L. Lin, Hsieh, S. L., and Wang, G. J.*, Development of double-generation gold nanoparticle chip-based dengue virus detection system combining fluorescence turn-on probes, Biosensors & Bioelectronics, 77, 90-98. (2016) (SCI, Impact Factor=7.78, 1/28).

2015

  1. Lee, B. Y., Li, C. W. and Wang, G. J.*, Nanoporous anodic aluminum oxide tube encapsulating a microporous chitosan/collagen composite for long-acting drug release, Biomedical Physics & Engineering Express, 1, 045004 (2015)
  2. Hsu, C. W., Feng, W. C., Su, F. C., and Wang, G. J.*, A novel electrochemical glucose biosensor with a silicon nanowire array electrode, J. Electrochemical Society, 162(10), B1-B5. (2015) (SCI, Impact Factor=3.259, 2/19)
  3. Hsieh, Y. D., Lee, M. Y., and Wang, G. J.*, Sb2S3 quantum-dot sensitized solar cells with silicon nanowire photoelectrode, Inter. J. of Photoenergy, Vol. 2015, Article ID 213858, 10 pages. (2015). (SCI, Impact Factor=1.277, 63/92)
  4. Liao, E. C, Chang, C. Y., Wu, C. C., Wang, G. J., Tsai, J. W.,  Association of single nucleotide polymorphisms in the MD-2 gene promoter region with Der p 2 allergy, Allergy Asthma Immunol Res. 7(3), 249-255 (2015) (SCI, Impact Factor=2.957)

2014

  1. Liu, H. C. and Wang, G. J.*, Superior antireflection coating for a silicon cell with a micro-nano hybrid structure, Inter. J. of Photoenergy, Vol. 2014, Article ID 807812, 8 pages. (2014). (SCI, Impact Factor=1.277, 63/92)
  2. Tung, Y. T., Wu, M. F., Wang, G. J.*, and Hsieh, S. L**, Nanostructured electrochemical biosensor for the detection of the weak binding between the Dengue Virus and the CLEC5A receptor, Nanomedicine: NBM, 10, 1335-1341. (2014) (SCI, Impact Factor=5.72, 11/128).
  3. Hsu, C. W., Li, C. W. and Wang, G. J.*, Fabrication of biocompatible high aspect ratio Au–Ni coaxial nanorod arrays using the electroless Galvanic displacement reaction method, RSC advances, 4, 12127-12132. (2014) (SCI, Impact Factor=3.108, 59/165).
  4. Hsu, C. W. and Wang, G. J.*, Highly sensitive glucose biosensor based on Au–Ni coaxial nanorod array having high aspect ratio, Biosensors & Bioelectronics, 56, 204-209. (2014) (SCI, Impact Factor=7.780, 1/28).
  5. Wu, J. Y., Li,C. W., Tsai, C. H., Chou, C. W., Chen, D. R., and Wang, G. J.*, Synthesis of antibacterial TiO2/PLGA composite biofilms, Nanomedicine: NBM, 10, 1097-1107, (2014) (SCI, IF=5.72, 11/128).
  6. Chin, Y. T., Liao, E. C., Wu, C. C., Wang, G. J.*, and Tsai, J. J.*, Detection of the haplotype mutations of the MD-2gene promoter associated with Der p2-induced allergy using a nanostructured biosensor, Inter. J. Nanomedicine, 9, 403-412. (2014) (SCI, Impact Factor=4.30, 37/256)
  7. Wu, C. C.*, Ku, B. C., Ko, C. H., Chiu, C. C., Wang, G. J., Yang, Y. H., Wu, S. J., Electrochemical impedance spectroscopy analysis of A-beta (1-42) peptide using a nanostructured biochip, Electrochimica Acta, 134, 249-257, (2014) (SCI, Impact Factor=4.798, 4/28).

2013

  1. Liu, H. C. and Wang, G. J.*, Fabrication of high anti-reflection nanowires on silicon using two-stage metal-assisted etching, Journal of Renewable and Sustainable Energy, 5, 053115. (2013) (SCI, Impact Factor=1.145, 68/90).
  2. Li, C. W. and Wang, G. J.*, A material-independent cell–environment niche based on micro-reciprocating motion for cell growth enhancement, Biofabrication, 5, 045001. (2013) (SCI, Impact Factor=5.240, 5/77).
  3. Chung, I. C., Li, C. W., and Wang, G. J.*, The influence of different nanostructured scaffolds on fibroblast growth, Science and Technology of Advanced Materials, 14, 044401. (2013) (SCI, Impact Factor=3.789, 54/274).
  4. Chin, Y. T., Liao, E. C., Wu, C. C., Wang, G. J.*, and Tsai, J. J.*, Label-free detection of single-nucleotide polymorphisms associated with myeloid differentiation-2 using a nanostructured biosensor, Biosensors & Bioelectronics, 49, 506-511. (2013) (SCI, Impact Factor=7.78, 1/28).
  5. Wang, H. W., Cheng, C. W., Li, C. W., Wu, P. H., and Wang, G. J.*, Hollow three-dimensional endothelialized microvessel networks based on femtosecond laser ablation, Biomedical Microdevices, 15, 879-885. (2013) (SCI, Impact Factor=2.062, 36/77).
  6. Liu, H. C., Tsai, C. C. and Wang, G. J.*, Glucose biosensors based on a gold nanodendrite modified screen-printed electrode, Nanotechnology, 24, 215101. (2013) (SCI, Impact Factor=3.44, 27/147).
  7. Tsai, J. J., Liu, Y. F., Liao, E. C., Chen, J. L, and Wang, G. J.*, Reduction of incubation time and enhancement of analyte adhesion uniformity of impedance biosensors using microvibration method, Sensors & Actuators B: Chemical, 178, 404-411. (2013) (SCI, Impact Factor=5.401, 2/58)
  8. Chou,C. W.*, Hsieh,H. H., Chen, K. S., Hong-Ru Lin, H. R., Wang, G. J., Chang, H. C., Pan, Y. L., Wei, Y. S., Chang, K. S., and Harn, Y. W., Biopolymer coated gold nanocrystals prepared using the green chemistry approach and their shape-dependent catalytic and surface-enhanced Raman scattering properties, Physical Chemistry Chemical Physics, 15, 11275-11286. (2013) (SCI, Impact Factor=4.123, 6/35).
  9. Lin, Y. W. and Wang, G. J.*, Dielectrophoresis measurement of bovine endothelial cells adhesion on different materials, Microsystem Technologies, 19, 945-955. (2013) (SCI, Impact Factor=1.195, 171/260)
  10. Tsai, Y. T., Chang, K. J., and Wang, G. J.*, Measurement and control of the ion diffusion coefficient in a nanochannel, Microsystem Technologies, 19, 937-944. (2013) (SCI, Impact Factor=1.195, 171/260)
  11. Tsai, C. C. and Wang, G. J.*, A glucose biosensor based on a 3D nanostructured gold electrode, J. Electrochemical Society, 160(1), B1-B5. (2013) (SCI, Impact Factor=3.259, 2/19)

2012

  1. Liu, Y. F., Tsai, J. J., Chin, Y. T., Liao, E. C., Wu, C. C., Wang, G. J.*, Detection of allergies using a silver nanoparticle modified nanostructured biosensor, Sensors & Actuators B: Chemical, 171-172, 1095-1100. (2012) (SCI, Impact Factor=5.401, 2/58)
  2. Wang, H. W., Cheng, C. W., Li, C. W., Chang, H. W., Wu, P. H., Wang, G. J.*, Fabrication of pillared PLGA microvessel scaffold using femtosecond laser ablation, Inter. J. Nanomedicine, 7, 1865-1873. (2012) (SCI, Impact Factor=4.30, 37/256)
  3. Chen, Y. S., Wu, C. C., Tsai, J. J., and Wang, G. J.*, An electrochemical impedimetric biosensor based on a nanostructured polycarbonate (PC) substrate, Inter. J. Nanomedicine, 7, 133-140 (2012) (SCI, Impact Factor=4.30, 37/256)
  4. Ho, J. Y. and Wang, G. J.*, Fabrication of high aspect ratio nanoporous array on silicon, Microsystem Technologies, 18, 1849-1856. (2012) (SCI, Impact Factor=1.195, 171/260)

Before 2011

  1. Tsai, J. J., Bau, I. J., Chen, H. T., Lin, Y. T., and Wang, G. J.*, A novel nanostructured biosensor for the detection of the dust mite antigen Der p2, Inter. J. Nanomedicine, 6, 1201-1208. (2011)
  2. Chang, C. Y. and Wang, G. J.*, Anodic Aluminum Oxide Diodes, Japanese Journal of Applied Physics, 50(7), 075201 (4 pages) (2011) (SCI, Impact Factor=1.122)
  3. Tubtimtae, A., Lee, M. W.*, and Wang, G. J., Ag2Se quantum-dot sensitized solar cells for full solar spectrum light harvesting, Journal of Power Sources, 196, 6603-6608. (2011)
  4. Lin, Y. H., Chang, K. J., and Wang, G. J.*, A Novel Chip-on-Glass method for Slim LCD Packaging, Microsystem Technologies, 17, 685-691. (2011)
  5. Wang, G. J.*, Lee, M. W., Chen, W. Z., Chen, Y. H., Chien, M. C., Yu, M. C., A Metal-Solution Field-Effect-Transistor Enhanced Proton-Motive-Force Driving Photovoltaic, IEEE Trans. on Nanotechnology, 10, 191-196. Cover page (2011)
  6. Wang, C. G. and Wang, G. J.*, A MOSFET-like infrared sensor for the enhancement of photoconductivity and photoresponsivity, Current Nanoscience, 6(6), 648-653. (2010)
  7. Wang, G. J.*, Lin, Y. C., and Hsu, S. h., The Fabrication of PLGA Microvessel Scaffolds with Nano-Patterned Inner Walls, Biomedical Microdevices, 12, 841-848. (2010). Wang, G. J.* and Chou, S. W., Electrophoretic deposition of uniformly distributed TiO2 nanoparticles using an anodic aluminum oxide template for efficient photolysis, Nanotechnology, 21, 115206, (2010)
  8. Hsu, C. W., Chou, Z. D., and Wang, G. J.*, Fabrication of High Aspect Ratio Alumina-Nickel Coaxial Nanorod Array by Electrodeposition, ASME/IEEE J. of Microelectromechnaical System, 19(4), 849-853 (2010)..
  9. Chen, Y. C., Chen, G. Y., Lin, Y. C., and Wang, G. J.*, A Lab-on-a-Chip Capillary Network for Red Blood Cell Hydrodynamics, Microfluidics and Nnaofluidics, 9, 585-591. (2010).
  10. Chen, G. Y., Lee, M. W., and Wang, G. J.*, Fabrication of Dye- Sensitized Solar Cells with A 3D Nanostructured Electrode, Inter. J. of Photoenergy, 2010, Article ID 585621, 7 pages, DOI:10.1155/2010/585621, (2010)
  11. Lai, M. H., Tubtimtae, A., Lee, M. W.*, Wang, G. J., ZnO-Nanorod Dye-Sensitized Solar Cells: New Structure without a Transparent Conducting Oxide Layer, Inter. J. of Photoenergy, 2010, Article ID 497095, 5 pages, , (2010)
  12. Tubtimtae, A., Wu, K. L., Tung, H. Y., Lee, M. W.*, Wang, G. J., Ag2S quantum dot-sensitized solar cells, Electrochemistry Communications, 12, 1158-1160 (2010)
  13. Wang, G. J.*, Lin, Y. C., Lee, J. W,, Hsueh, C. C., Hsu, S. h, Hung, H. S., Fabrication of Orderly Nanostructured PLGA Scaffolds Using Anodic Aluminum Oxide Templates, Biomedical Microdevices, 11, 843-850. (2009)
  14. Chen, H. T. and Wang, G. J.*, Fabrication of 3D Nano-structured ITO Films by RF Magnetron Sputtering, Current Nanoscience, 5(3), 297-301. (2009)
  15. Wang, G. J.*, Lee, M. W., Chen, Y. H., A TiO2/CNT coaxial structure and standing CNT array laminated photocatalyst to enhance the photolysis efficiency of TiO2, Photochemistry and Photobiology, 84, 1493-1499. (2008)
  16. Chien, M. C., Wang, G. J.*, Yu. M. C., Nanopore Size Estimation Using Electrochemical ImpedanceSpectroscopy Analysis, Japanese Journal of Applied Physics, 47(9), 7459-7463. (2008)
  17. Wang, G. J.*, Chen, H. T., Yang, H., Fabrication of crystalline indium tin oxide nanobaskets electrode using AAO template, Japanese Journal of Applied Physics, 47(7), 5727-5729. (2008)
  18. Wang, G. J.*, Ho, K. H., Hsueh, C. C., Biodegradable polylactic acid (PLA) microstructures for scaffold applications, Microsystem Technologies, 14, 989-993. (2008)
  19. Wang, G. J.*, Chen, W. Z., Chang, K., A two-step etching method to fabricate nanopores in silicon, Microsystem Technologies, 14, 925-927. (2008)
  20. Wang, G. J.*, Hsueh, C. C., Hsu, S. H., Hung, H. S., “Fabrication of PLGA Microvessel Scaffolds with Circular Microchannels Using Soft Lithography,” Journal of Micromechanics and Microengineering, Vol. 17, pp. 2000-2005. (2007)
  21. Chien, M. C., Wang, G. J.*, Yu. W. C., “Modeling Ion Diffusion Current in a Nanochannel Using Infinitesimal Distribution RC Circuits,” Japanese Journal of Applied Physics, Vol. 46, No. 11, pp. 7436-7440. (2007)
  22. Wang, G. J.*, Ho, K. H., Hsu, S. H., Wang, K. P., “Microvessel Scaffold with Circular Microchannels by Photoresist Melting,” Biomedical Microdevices, Vol. 9, pp. 657-663. (2007)
  23. Wang, G. J.*, Lin, Y. C., Lin, G. S., “Ultra Fine Pitch Flat Panel Display Packaging Using 3mm Conductive Particles,” Microsystem Technologies, Vol. 13, No. 11-12. pp. 1471-1476. (2007)
  24. Fan, J. Y., Chien, M. C, Wang, G. J.*, “Experimental Investigation on the Bi-directional Growing Mechanism of the Foils Laminate Approach in AAO Fabrication,” Nanoscale Research Letters, Vol. 2, No. 1, pp. 49-53. (2007)
  25. Wang, G. J.*, Lin, Y. C., Lin, G. S., “A Novel Contact Resistance Model of Anisotropic Conductive Film for FPD Packaging,” Microsystem Technologies, Vol. 13, No. 11-12. pp. 1477-1482. (2007)
  26. Wang, G. J.*, Lin, B. S. and Chang, K., “In-Situ Neural Network Process Controller for Copper Chemical Mechanical Polishing,” International Journal of Advanced Manufacturing Technology, Vol. 32, pp. 42-54. (2007)
  27. Wang, G. J.*, Chang, J. H., and Yang H., “Triplex-Pumping CD-Like Microfluidic Platform with Parabolic Microchannels,” Microsystem Technologies, Vol. 12, No. 10-11. pp. 899-905. (2006)
  28. Yu, W. C. and Wang, G. J.*, “Discrete Sliding Mode Controller Design Based on the LQR Suboptimal Approach with Application on AC Servo Motor,” Journal of Chinese Institute of Engineers, Vol. 29, No 5, pp. 873-882. (2006)
  29. Wang, G. J.* and Hsu, W. H., “PET Laminated Thin-Film Capillary Electrophoresis Chips by Sandwiching Method,” International Journal of Advanced Manufacturing Technology, Vol. 30, No 1-2, pp. 87-91. (2006)
  30. Chen, S. N., Wang, G. J.* and M. C. Chien, “Analytical modeling of piezoelectric vibration-induced micro power generator, “Mechatronics, Vol. 16, pp 379-387. (2006)
  31. Wang, G. J.*, Yu, W. C., Lin, Y. H., Yang, H., “Modeling and Fabrication of a Piezoelectric Vibration-Induced Micro Power Generator,” Journal of Chinese Institute of Engineers, Vol. 29, No. 4. pp. 697-706. (2006)
  32. Wang, G. J.* and Liu, H. R., “Piezoelectric Actuated Multiple Channels Optical Switch,” Analog integrated circuits and signal processing, Vol. 48, No. 1, pp15-20. (2006)
  33. Wang, G. J.* and Peng, C. S., “Control Porous Pattern of Anodic Aluminum Oxide by Foils Laminate Approach,” Journal of Nanoscience and Nanotechnology, Vol. 6, No. 4, pp 1004-1008. (2006)
  34. Wang, G. J.* and Yu, C. H., “Developing a Neural Network Based Run-To-Run Process Controller For Chemical Mechanical Planarization,” International Journal of Advanced Manufacturing Technology, Vol. 28, No. 9, pp 899-908. (2006)
  35. Wang, G. J.* and Hsu, Y. F., “Structure Optimization of Microvascular Scaffolds” Biomedical Microdevices, Vol. 8, No. 1, pp 51-58. (2006)
  36. Wang, G. J.*, Hsu, Y. F., Hsu, S. H., Horng, R. H. “JSR Photolithography Based Microvascular Fabrication and Cell Seeding” Biomedical Microdevices, Vol. 8, No. 1, pp 17-23. (2006)
  37. Chang, Y. Z., Yang, M. W., Wang, G. J.*, “A New Mass Spectrometry Electro-Spray Tip Based on Precise Mechanical Micro Machining,” Analytical and Bioanalytical Chemistry, Vol. 383, No. 1, pp. 76-82. (2005)
  38. Wang, G. J.*, Chen, C. L., Hsu, S. H., and Chiang, Y. L., “Bio-MEMS Fabricated Artificial Vascular Network for Tissue Engineering,” Microsystem Technologies, Vol. 12, No. 1-2, pp. 120-127. (2005)
  39. Wang, G. J.* and Chou, M. H., “A Neural-Taguchi Based Quasi Time-Optimal Control Strategy For Chemical Mechanical Polishing Processes,” International Journal of Advanced Manufacturing Technology, Vol. 26, No. 7-8, pp. 759-765. (2005)
  40. Wang, G. J.*, Lee, C. K., Hsu, C. C.,” Toward a Comprehensively Interdisciplinary Nanoscience and Nanotechnology Personnel Training Program In Taiwan,” INNOVATIONS 2005-World Innovations in Engineering Education and Research, Chapter IV. (2005)
  41. Wang, G. J.*, Cheng, Y. D, Chang, K.,” A New Neural Fuzzy Control System with Heuristic Learning,” International Journal of Fuzzy Systems, Vol. 7, No. 4, pp. 158-168. (2005)
  42. Wang, G. J.*, Yang, M. W., Chang, Y. Z. “Dead Volume Free Micro-machined Electro-spray Chip for Mass Spectrometry,” Biomedical Microdevices, Vol. 6, No. 2. pp. 159-164 (2004)
  43. Yu, W. C. and Wang, G. J.*, “Discrete Sliding Mode Control with Forgetting Dynamic Sliding Surface,“ Mechatronics, Vol. 14, pp. 737-755. (2004)
  44. Wang, G. J.*, Hsu, W. H., Chang, Y. Z., Yang, H. H. “Centrifugal and Electric Field Forces Dual-Pumping CD-Like Microfluidic Platform for Biomedical Separation,” Biomedical Microdevices, Vol. 6, No. 1, pp. 47-53. (2004)
  45. Wang, G. J.*, and Song, S. W., Yu, W. C., “A New Discrete Dynamic Sliding Mode Controller for Singular Perturbed Servo Systems,” Journal of Chinese Society of Mechanical Engineers, Vol. 25, No. 1, pp 41-50. (2004)
  46. Wang, G. J.* and Chou, M. H., Chang K., “New Orthogonalization And Conjugate Descendent Based Parameter Setting-Free Methods For The Backpropagation Algorithm,” Journal of Chinese Society of Mechanical Engineers, Vol. 24, No 5, pp. 499-505. (2003)
  47. Wang, G. J.*, Wang, S. Y., and Chin, C. H., “Fabrication and Modeling of the Gray-scale Mask Based Aspheric Refraction Microlens Array,” JSME International Journal, Series C, Vol. 46, No. 4, pp. 1958-1603 (2003)
  48. Yu, W. C. and Wang, G. J.*, “Discrete-Type Heuristic Self-Tuning PID Controller,“ Journal of Chinese Society of Mechanical Engineers, Vol. 24, No 2, pp. 181-186. (2003)
  49. Wang, G. J.*, Wu, J. G., Chang K., “A New Neural Network Based Parameter Optimization Method,” Journal of Chinese Society of Mechanical Engineers, Vol. 24, No 2, pp. 99-109. (2003)
  50. Wang, G. J.*, Fong, T. T., and K. J. Chang, “Neural Network-Based Self-Tuning PI Controller for Precise Motion Control of PMAC Motors,” IEEE Transaction on Industrial Electronics, Vol. 48, No. 2, pp 408-416. (2001)
  51. Wang, G. J.*, Chen, J. L., and Hwang, J. Y., “New Optimization Strategy for Chemical Mechanical Polishing Process,” JSME International Journal, Series C, Vol. 44, No. 2, pp. 534-543. (2001)
  52. Wang, G. J.*, and Chen, J. J., “Cascade Steepest Descendant Learning Algorithm for Multilayer Feedforward Neural Network,” JSME International Journal, Series C, Vol.43, No. 2, pp 350-358. (2000)
  53. Wang, G. J.*, and Cheng, T. C., “A Robust Self-Tuning Learning Algorithm for Multilayer Feedforward Neural Network,” Neurocomputing, Vol. 25, pp167-189.  (1999)
  54. Wang, G. J.*, and Wang, C. C., "Reverse Engineering of Sculptured Surface by Four-Axis Non-Contacting Scanning," International Journal of Advanced Manufacturing Technology, Vol. 15, No. 5. (1999)
  55. Wang, G. J.*, Luh, C. F., and Wang, C. C., "Intelligent 3D CAD Data Extracting System," JSME International Journal, Series C, Vol.41, No. 4, pp. 912-921. (1998)
  56. Wang, G. J.*, and Yang, Y. Z., Chang, K., "A MDRS Network Based Intelligent Vision System," the International Journal of Knowledge-Based Intelligent Engineering Systems, Vol. 2, NO 1, pp. 17-31. (1998)
  57. Wang, G. J.*, Tsai, J. C., Tzeng, P. C., and Cheng, T. C., "Neural-Taguchi Method for Robust Design Analysis," Journal of the Chinese Society of Mechanical Engineers Vol. 19, NO 2. pp. 223-230. (1998)
  58. Wang, G. J.*, and Cheng, C. C., "A Fast Multilayer Neural Network Training Algorithm Based on the Layer-By-Layer Optimizing Procedures," IEEE Tran. on Neural Network, Vol. 7, No. 3, pp. 768-775  (1996)
  59. 王國禎*, 陳琮祺, 1996, " 類神經網路適應學習演算法," 興大工程學報, Vol. 7, No. 2, pp. 1-7. (1996)
  60. 王國禎*,黃仲麒, " 渦輪噴射引擎之類神經網路全域控制," 中國航空太空學刊, Vol. 28, No. 2, pp. 137-145. (1996)
  61. 王國禎*,黃仲麒, " 雙軸渦輪扇引擎之類神經網路控制器," 中國航空太空學刊, Vol. 28, No. 3, pp. 231-239. (1996)

(B)   Book Chapter

1.      Lee, J. W. and Wang, G. J.*, “Tissue Scaffolding Devices,” MEMS for biomedical applications, Woodhead Publishing Limited, (2012, 07).

 

(C) Conference proceedings